Blar i Bergen Open Research Archive på forfatter "Heimli, Marte"
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Characterization of regulatory T cells in Autoimmune Polyendocrine Syndrome type I, a model disease for autoimmunity
Heimli, Marte (Master thesis, 2018-12-21)The T and B lymphocytes of the adaptive immune system face the challenge of correctly recognizing antigens originating from a vast number of rapidly evolving pathogens, while ignoring those pertaining to the host itself. ... -
Transcriptional Changes in Regulatory T Cells From Patients With Autoimmune Polyendocrine Syndrome Type 1 Suggest Functional Impairment of Lipid Metabolism and Gut Homing
Berger, Amund Holte; Bratland, Eirik; Sjøgren, Thea; Heimli, Marte; Tyssedal, Torgeir; Bruserud, Øyvind; Johansson, Stefan; Husebye, Eystein Sverre; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe (Journal article; Peer reviewed, 2021)Autoimmune polyendocrine syndrome type I (APS-1) is a monogenic model disorder of organ-specific autoimmunity caused by mutations in the Autoimmune regulator (AIRE) gene. AIRE facilitates the expression of organ-specific ...